Diabetes & Metabolism Journal

Editorial

Combining Ezetimibe and Rosuvastatin: Impacts on Insulin Sensitivity and Vascular Inflammation in Patients with Type 2 Diabetes Mellitus: Eun Roh; Diabetes Metab J. 2024;48(1):55-58. Published online January 29, 2024; DOI: https://doi.org/10.4093/dmj.2023.0442

1,251 View
164 Download

PDF PubReader ePub

Letter

Association of Myosteatosis with Nonalcoholic Fatty Liver Disease, Severity, and Liver Fibrosis Using Visual Muscular Quality Map in Computed Tomography (Diabetes Metab J 2023;47:104-17): Eun Roh; Diabetes Metab J. 2023;47(2):301-303. Published online March 15, 2023; DOI: https://doi.org/10.4093/dmj.2023.0051

1,407 View
112 Download

PDF PubReader ePub

Short Communication

Technology/Device
Comparison of Laser and Conventional Lancing Devices for Blood Glucose Measurement Conformance and Patient Satisfaction in Diabetes Mellitus: Jung A Kim, Min Jeong Park, Eyun Song, Eun Roh, So Young Park, Da Young Lee, Jaeyoung Kim, Ji Hee Yu, Ji A Seo, Kyung Mook Choi, Sei Hyun Baik, Hye Jin Yoo, Nan Hee Kim; Diabetes Metab J. 2022;46(6):936-940. Published online March 30, 2022; DOI: https://doi.org/10.4093/dmj.2021.0293

5,305 View
256 Download
1 Web of Science
1 Crossref

Abstract PDF PubReader ePub

Self-monitoring of capillary blood glucose is important for controlling diabetes. Recently, a laser lancing device (LMT-1000) that can collect capillary blood without skin puncture was developed. We enrolled 150 patients with type 1 or 2 diabetes mellitus. Blood sampling was performed on the same finger on each hand using the LMT-1000 or a conventional lancet. The primary outcome was correlation between glucose values using the LMT-1000 and that using a lancet. And we compared the pain and satisfaction of the procedures. The capillary blood sampling success rates with the LMT-1000 and lancet were 99.3% and 100%, respectively. There was a positive correlation (r=0.974, P<0.001) between mean blood glucose levels in the LMT-1000 (175.8±63.0 mg/dL) and conventional lancet samples (172.5±63.6 mg/dL). LMT-1000 reduced puncture pain by 75.0% and increased satisfaction by 80.0% compared to a lancet. We demonstrated considerable consistency in blood glucose measurements between samples from the LMT-1000 and a lancet, but improved satisfaction and clinically significant pain reduction were observed with the LMT-1000 compared to those with a lancet.

Citations

Citations to this article as recorded by

Comparison between a laser-lancing device and automatic incision lancet for capillary blood sampling from the heel of newborn infants: a randomized feasibility trial
Chul Kyu Yun, Eui Kyung Choi, Hyung Jin Kim, Jaeyoung Kim, Byung Cheol Park, Kyuhee Park, Byung Min Choi
Journal of Perinatology.2024;[Epub] CrossRef

Original Article

Cardiovascular Risk/Epidemiology
Myocardial Infarction, Stroke, and All-Cause Mortality according to Low-Density Lipoprotein Cholesterol Level in the Elderly, a Nationwide Study: You-Bin Lee, Minji Koo, Eunjin Noh, Soon Young Hwang, Jung A Kim, Eun Roh, So-hyeon Hong, Kyung Mook Choi, Sei Hyun Baik, Geum Joon Cho, Hye Jin Yoo; Diabetes Metab J. 2022;46(5):722-732. Published online March 8, 2022; DOI: https://doi.org/10.4093/dmj.2021.0225

7,033 View
331 Download
6 Web of Science
6 Crossref

Abstract PDF Supplementary Material PubReader ePub

Background
We assessed the myocardial infarction (MI), stroke, and all-cause death risks during follow-up according to the low-density lipoprotein cholesterol (LDL-C) levels among older adults.
Methods
The Korean National Health Insurance Service datasets (2002 to 2020) were used for this population-based cohort study. The hazards of MI, stroke, and all-cause mortality during follow-up were analyzed according to LDL-C level in individuals aged ≥65 years without baseline cardiovascular diseases (n=1,391,616).
Results
During a mean 7.55 years, 52,753 MIs developed; 84,224 strokes occurred over a mean 7.47 years. After a mean 8.50 years, 233,963 died. A decrease in LDL-C was associated with lower hazards of MI and stroke. The decreased hazard of stroke in lower LDL-C was more pronounced in statin users, and individuals with diabetes or obesity. The hazard of all-cause death during follow-up showed an inverted J-shaped pattern according to the LDL-C levels. However, the paradoxically increased hazard of mortality during follow-up in lower LDL-C was attenuated in statin users and individuals with diabetes, hypertension, or obesity. In statin users, lower LDL-C was associated with a decreased hazard of mortality during follow-up.
Conclusion
Among the elderly, lower LDL-C was associated with decreased risks of MI and stroke. Lower LDL-C achieved by statins in the elderly was associated with a decreased risk of all-cause death during follow-up, suggesting that LDL-C paradox for the premature death risk in the elderly should not be applied to statin users. Intensive statin therapy should not be hesitated for older adults with cardiovascular risk factors including diabetes.

Citations

Citations to this article as recorded by

Combination of low- or moderate-intensity statin and ezetimibe vs. high-intensity statin monotherapy on primary prevention of cardiovascular disease and all-cause death: a propensity-matched nationwide cohort study
Ji Eun Jun, In-Kyung Jeong, Kyu Jeong Ahn, Ho Yeon Chung, You-Cheol Hwang
European Journal of Preventive Cardiology.2024;[Epub] CrossRef
Associations of Low-density Lipoprotein Cholesterol With All-cause and Cause-specific Mortality in Older Adults in China
Wenqing Ni, Yuebin Lv, Xueli Yuan, Yan Zhang, Hongmin Zhang, Yijing Zheng, Xiaoming Shi, Jian Xu
The Journal of Clinical Endocrinology & Metabolism.2024;[Epub] CrossRef
The relationship of low-density lipoprotein cholesterol and all-cause or cardiovascular mortality in patients with type 2 diabetes: a retrospective study
Chin-Huan Chang, Shu-Tin Yeh, Seng-Wei Ooi, Chung-Yi Li, Hua-Fen Chen
PeerJ.2023; 11: e14609. CrossRef
ERCC1 polymorphism and its expression associated with ischemic stroke in Chinese population
Xiao-Dong Deng, Jian-Lin Ke, Tai-Yu Chen, Qin Gao, Zhuo-Lin Zhao, Wei Zhang, Huan Liu, Ming-Liang Xiang, Li-Zhen Wang, Ying Ma, Yun Liu
Frontiers in Neurology.2023;[Epub] CrossRef
New, Novel Lipid-Lowering Agents for Reducing Cardiovascular Risk: Beyond Statins
Kyuho Kim, Henry N. Ginsberg, Sung Hee Choi
Diabetes & Metabolism Journal.2022; 46(4): 517. CrossRef
Association between the Diabetes Drug Cost and Cardiovascular Events and Death in Korea: A National Health Insurance Service Database Analysis
Seung Min Chung, Ji-In Lee, Eugene Han, Hyun-Ae Seo, Eonju Jeon, Hye Soon Kim, Ji Sung Yoon
Endocrinology and Metabolism.2022; 37(5): 759. CrossRef

Short Communication

Basic Research
GPR40 Agonism Modulates Inflammatory Reactions in Vascular Endothelial Cells: Joo Won Kim, Eun Roh, Kyung Mook Choi, Hye Jin Yoo, Hwan-Jin Hwang, Sei Hyun Baik; Diabetes Metab J. 2022;46(3):506-511. Published online January 24, 2022; DOI: https://doi.org/10.4093/dmj.2021.0092

4,758 View
229 Download
8 Web of Science
7 Crossref

Abstract PDF PubReader ePub

Endothelial dysfunction is strongly linked with inflammatory responses, which can impact cardiovascular disease. Recently, G protein-coupled receptor 40 (GPR40) has been investigated as a modulator of metabolic stress; however, the function of GPR40 in vascular endothelial cells has not been reported. We analyzed whether treatment of GPR40-specific agonists modulated the inflammatory responses in human umbilical vein endothelial cells (HUVECs). Treatment with LY2922470, a GPR40 agonist, significantly reduced lipopolysaccharide (LPS)-mediated nuclear factor-kappa B (NF-κB) phosphorylation and movement into the nucleus from the cytosol. However, treatment with another GPR40 agonist, TAK875, did not inhibit LPS-induced NF-κB activation. LPS treatment induced expression of adhesion molecules vascular cell adhesion molecule-1 (VCAM-1) and intercellular adhesion molecule-1 (ICAM-1) and attachment of THP-1 cells to HUVECs, which were all decreased by LY2922470 but not TAK875. Our results showed that ligand-dependent agonism of GPR40 is a promising therapeutic target for overcoming inflammatory reactions in the endothelium.

Citations

Citations to this article as recorded by

Synthetic GPR40/FFAR1 agonists: An exhaustive survey on the most recent chemical classes and their structure-activity relationships
Abhik Paul, Sourin Nahar, Pankaj Nahata, Arnab Sarkar, Avik Maji, Ajeya Samanta, Sanmoy Karmakar, Tapan Kumar Maity
European Journal of Medicinal Chemistry.2024; 264: 115990. CrossRef
Metabolite-sensing GPCRs in rheumatoid arthritis
Xuezhi Yang, Wankang Zhang, Luping Wang, Yingjie Zhao, Wei Wei
Trends in Pharmacological Sciences.2024; 45(2): 118. CrossRef
GPR40 deficiency worsens metabolic syndrome‐associated periodontitis in mice
Yanchun Li, Zhongyang Lu, Cameron L. Kirkwood, Keith L. Kirkwood, Stephen A. Wank, Ai‐Jun Li, Maria F. Lopes‐Virella, Yan Huang
Journal of Periodontal Research.2023; 58(3): 575. CrossRef
Signaling pathways and intervention for therapy of type 2 diabetes mellitus
Rong Cao, Huimin Tian, Yu Zhang, Geng Liu, Haixia Xu, Guocheng Rao, Yan Tian, Xianghui Fu
MedComm.2023;[Epub] CrossRef
G Protein-Coupled Receptor 40 Agonist LY2922470 Alleviates Ischemic-Stroke-Induced Acute Brain Injury and Functional Alterations in Mice
Yingyu Lu, Wanlu Zhou, Qinghua Cui, Chunmei Cui
International Journal of Molecular Sciences.2023; 24(15): 12244. CrossRef
AM1638, a GPR40-Full Agonist, Inhibited Palmitate- Induced ROS Production and Endoplasmic Reticulum Stress, Enhancing HUVEC Viability in an NRF2-Dependent Manner
Hwan-Jin Hwang, Joo Won Kim, SukHwan Yun, Min Jeong Park, Eyun Song, Sooyeon Jang, Ahreum Jang, Kyung Mook Choi, Sei Hyun Baik, Hye Jin Yoo
Endocrinology and Metabolism.2023; 38(6): 760. CrossRef
Learn from failures and stay hopeful to GPR40, a GPCR target with robust efficacy, for therapy of metabolic disorders
Hong-Ping Guan, Yusheng Xiong
Frontiers in Pharmacology.2022;[Epub] CrossRef

Editorial

The Role of Adipose Tissue Lipolysis in Diet-Induced Obesity: Focus on Vimentin: Eun Roh, Hye Jin Yoo; Diabetes Metab J. 2021;45(1):43-45. Published online January 22, 2021; DOI: https://doi.org/10.4093/dmj.2020.0293

3,994 View
142 Download
2 Web of Science
3 Crossref

PDF PubReader ePub

Citations

Citations to this article as recorded by

Bioinformatics and Next-Generation Data Analysis for Identification of Genes and Molecular Pathways Involved in Subjects with Diabetes and Obesity
Prashanth Ganekal, Basavaraj Vastrad, Satish Kavatagimath, Chanabasayya Vastrad, Shivakumar Kotrashetti
Medicina.2023; 59(2): 309. CrossRef
Selegiline Modulates Lipid Metabolism by Activating AMPK Pathways of Epididymal White Adipose Tissues in HFD-Fed Obese Mice
Hye-Young Joung, Jung-Mi Oh, Min-Suk Song, Young-Bae Kwon, Sungkun Chun
Pharmaceutics.2023; 15(11): 2539. CrossRef
An analogue of the Prolactin Releasing Peptide reduces obesity and promotes adult neurogenesis
Sara KM Jörgensen, Alena Karnošová, Simone Mazzaferro, Oliver Rowley, Hsiao-Jou Cortina Chen, Sarah J Robbins, Sarah Christofides, Florian T Merkle, Lenka Maletínská, David Petrik
EMBO Reports.2023; 25(1): 351. CrossRef

Original Articles

Metabolic Risk/Epidemiology
Age- and Sex-Related Differential Associations between Body Composition and Diabetes Mellitus: Eun Roh, Soon Young Hwang, Jung A Kim, You-Bin Lee, So-hyeon Hong, Nam Hoon Kim, Ji A Seo, Sin Gon Kim, Nan Hee Kim, Kyung Mook Choi, Sei Hyun Baik, Hye Jin Yoo; Diabetes Metab J. 2021;45(2):183-194. Published online June 16, 2020; DOI: https://doi.org/10.4093/dmj.2019.0171

7,450 View
236 Download
3 Web of Science
5 Crossref

Graphical Abstract Abstract PDF Supplementary Material PubReader ePub

Background

The age- and sex-related differences on the impacts of body composition on diabetes mellitus (DM) remain uncertain.

Methods

The fourth and fifth Korea National Health and Nutrition Examination Survey included 15,586 subjects over 30 years of age who completed dual-energy X-ray absorptiometry. We conducted a cross-sectional study to investigate whether muscle mass index (MMI), defined as appendicular skeletal muscle divided by body mass index (BMI), and fat mass index (FMI), defined as trunk fat mass divided by BMI, were differently associated with DM according to age and sex.

Results

In multivariate logistic regression, the risk for DM significantly increased across quartiles of FMI in men aged ≥70. Meanwhile, MMI showed a protective association with DM in men of the same age. The odds ratios (ORs) for the highest quartile versus the lowest quartile of FMI and MMI were 3.116 (95% confidence interval [CI], 1.405 to 6.914) and 0.295 (95% CI, 0.157 to 0.554), respectively. In women, the ORs of DM was significantly different across FMI quartiles in those over age 50. The highest quartile of FMI exhibited increased ORs of DM in subjects aged 50 to 69 (OR, 1.891; 95% CI, 1.229 to 2.908) and ≥70 (OR, 2.275; 95% CI, 1.103 to 4.69) compared to lowest quartile. However, MMI was not significantly associated with DM in women of all age groups.

Conclusion

Both FMI and MMI were independent risk factors for DM in men aged 70 years or more. In women over 50 years, FMI was independently associated with DM. There was no significant association between MMI and DM in women.

Citations

Citations to this article as recorded by

Research Progress on Correlation between Body Composition Changes and Disease Pro-gression of Type 2 Diabetes
敏张
Advances in Clinical Medicine.2024; 14(03): 936. CrossRef
Low Skeletal Muscle Mass Accompanied by Abdominal Obesity Additively Increases the Risk of Incident Type 2 Diabetes
Ji Eun Jun, Seung-Eun Lee, You-Bin Lee, Gyuri Kim, Sang-Man Jin, Jae Hwan Jee, Jae Hyeon Kim
The Journal of Clinical Endocrinology & Metabolism.2023; 108(5): 1173. CrossRef
Is imaging-based muscle quantity associated with risk of diabetes? A meta-analysis of cohort studies
Shanhu Qiu, Xue Cai, Yang Yuan, Bo Xie, Zilin Sun, Tongzhi Wu
Diabetes Research and Clinical Practice.2022; 189: 109939. CrossRef
Whole and segmental body composition changes during mid-follicular and mid-luteal phases of the menstrual cycle in recreationally active young women
Şükran Nazan Koşar, Yasemin Güzel, Mehmet Gören Köse, Ayşe Kin İşler, Tahir Hazır
Annals of Human Biology.2022; 49(2): 124. CrossRef
Body Composition and Diabetes
Hye Jin Yoo
The Journal of Korean Diabetes.2021; 22(4): 238. CrossRef

Prevalence and Management of Dyslipidemia in Korea: Korea National Health and Nutrition Examination Survey during 1998 to 2010: Eun Roh, Seung-Hyun Ko, Hyuk-Sang Kwon, Nan Hee Kim, Jae Hyeon Kim, Chul Sik Kim, Kee-Ho Song, Jong Chul Won, Dae Jung Kim, Sung Hee Choi, Soo Lim, Bong-Yun Cha; Diabetes Metab J. 2013;37(6):433-449. Published online December 12, 2013; DOI: https://doi.org/10.4093/dmj.2013.37.6.433

5,153 View
39 Download
73 Crossref

Abstract PDF PubReader

Background

Dyslipidemia is a major risk factor of cardiovascular disease. The aim of this study was to investigate the changing trends in the prevalence and management status of dyslipidemia among Korean adults.

Methods

The prevalence of dyslipidemia and the rates of awareness, treatment, and control of dyslipidemia were investigated in adults aged ≥20 years from the Korea National Health and Nutrition Surveys (KNHANES) 1998 to 2010. The updated National Cholesterol Education Program criteria was used, which define dyslipidemia as having one or more of the following lipid abnormalities: hypercholesterolemia (total cholesterol ≥240 mg/dL or diagnosis of dyslipidemia or use of lipid-lowering drugs), hypertriglyceridemia (≥150 mg/dL), hyper-low density lipoprotein (LDL) cholesterolemia (≥160 mg/dL or diagnosis of dyslipidemia or use of lipid-lowering drugs), and hypo-high density lipoprotein (HDL)-cholesterolemia (<40 mg/dL in men and <50 mg/dL in women).

Results

The number of participants was 6,921, 4,894, 5,312, 2,733, 6,295, 6,900, and 5,738 in KNHANES 1998, 2001, 2005, 2007, 2008, 2009, and 2010, respectively. Age-standardized prevalence rates of dyslipidemia were 54.0%, 65.8%, 66.5%, 60.6%, 58.7%, 58.9%, and 59.0% in 1998, 2001, 2005, 2007, 2008, 2009, and 2010, respectively. Hypertriglyceridemia and hypo-HDL-cholesterolemia were the two most frequent lipid abnormalities. The overall prevalence of hypercholesterolemia and hyper-LDL-cholesterolemia increased by 1.36- and 1.35-fold in 2010 compared with 2007, respectively. Awareness, treatment, and control rates of dyslipidemia improved over the period of surveys in both sexes. In 2010, about 30% of dyslipidemic patients who received lipid-lowering treatment reached target levels.

Conclusion

Although the management status of dyslipidemia has improved during recent years, effective strategy is required for achieving better prevention, treatment, and control of dyslipidemia.

Citations

Citations to this article as recorded by

SCORE and SCORE2 in East Asian Population
JungMin Choi, Soseul Sung, Sue K. Park, Seyong Park, Hyoyeong Kim, Myeong-Chan Cho, Bryan Williams, Hae-Young Lee
JACC: Asia.2024; 4(4): 265. CrossRef
Statin use and the risk of hepatocellular carcinoma among patients with chronic hepatitis B: an emulated target trial using longitudinal nationwide population cohort data
Dong Hyun Sinn, Danbee Kang, Yewan Park, Hyunsoo Kim, Yun Soo Hong, Juhee Cho, Geum-Youn Gwak
BMC Gastroenterology.2023;[Epub] CrossRef
Menopause management: A manual for primary care practitioners and nurse practitioners
Neelam Aggarwal, Meeta Meeta, Nirja Chawla
Journal of Mid-life Health.2022; 13(5): 2. CrossRef
New, Novel Lipid-Lowering Agents for Reducing Cardiovascular Risk: Beyond Statins
Kyuho Kim, Henry N. Ginsberg, Sung Hee Choi
Diabetes & Metabolism Journal.2022; 46(4): 517. CrossRef
Status of dyslipidemia management and statin undertreatment in Korean cancer survivors: A Korean National Health and Nutrition Examination Survey study
Sujeong Shin, Dong Wook Shin, In Young Cho, Su-Min Jeong, Hyein Jung
European Journal of Preventive Cardiology.2021; 28(8): 864. CrossRef
Triglyceride glucose (TyG) index as a predictor of incident type 2 diabetes among nonobese adults: a 12-year longitudinal study of the Korean Genome and Epidemiology Study cohort
Byoungjin Park, Hye Sun Lee, Yong-Jae Lee
Translational Research.2021; 228: 42. CrossRef
Temporal change in the diagnosis and treatment rates of osteoporosis: results from the Korea National Health and Nutrition Examination Survey
Y. J. Choi, H.-B. Shin, B. Park, D. J. Kim, Y.-S. Chung
Osteoporosis International.2021; 32(9): 1777. CrossRef
Hypertriglyceridemia and Other Plasma Lipid Profile Abnormalities among People Living with Diabetes Mellitus in Ethiopia: A Systematic Review and Meta-Analysis
Baye Dagnew, Yigizie Yeshaw, Demeke Geremew, Dessie Abebaw Angaw, Henok Dagne, Mekuriaw Alemayehu, Meseret Derbew Molla, Yonas Akalu, Carlos R. Bueno Junior
BioMed Research International.2021; 2021: 1. CrossRef
Triglyceride to HDL-Cholesterol Ratio and the Incident Risk of Ischemic Heart Disease Among Koreans Without Diabetes: A Longitudinal Study Using National Health Insurance Data
Byoungjin Park, Dong Hyuk Jung, Hye Sun Lee, Yong Jae Lee
Frontiers in Cardiovascular Medicine.2021;[Epub] CrossRef
Three Musketeers for Lowering Cholesterol: Statins, Ezetimibe and Evolocumab
Qian Xu, Yiming Deng, Jun Xiao, Xiangrui Liu, Min Zhou, Zhong Ren, Juan Peng, Yaling Tang, Zhisheng Jiang, Zhihan Tang, Lushan Liu
Current Medicinal Chemistry.2021; 28(5): 1025. CrossRef
Achievement of LDL-C Targets Defined by ESC/EAS (2011) Guidelines in Risk-Stratified Korean Patients with Dyslipidemia Receiving Lipid-Modifying Treatments
Ye Seul Yang, Seo Young Lee, Jung-Sun Kim, Kyung Mook Choi, Kang Wook Lee, Sang-Chol Lee, Jung Rae Cho, Seung-Jin Oh, Ji-Hyun Kim, Sung Hee Choi
Endocrinology and Metabolism.2020; 35(2): 367. CrossRef
Statin Use and the Risk of Hepatocellular Carcinoma in Patients With Chronic Hepatitis B
Myung Ji Goh, Dong Hyun Sinn, Seonwoo Kim, Sook Young Woo, Hyun Cho, Wonseok Kang, Geum‐Youn Gwak, Yong‐Han Paik, Moon Seok Choi, Joon Hyeok Lee, Kwang Cheol Koh, Seung Woon Paik
Hepatology.2020; 71(6): 2023. CrossRef
Low-density lipoprotein cholesterol goal attainment rates in high-risk patients with cardiovascular diseases and diabetes mellitus in Korea: a retrospective cohort study
Ye Seul Yang, Bo Ram Yang, Mi-Sook Kim, Yunji Hwang, Sung Hee Choi
Lipids in Health and Disease.2020;[Epub] CrossRef
Prevalencia de hipertrigliceridemia en adultos y factores cardiometabólicos asociados. Estudio SIMETAP-HTG
Antonio Ruiz-García, Ezequiel Arranz-Martínez, Beatriz López-Uriarte, Montserrat Rivera-Teijido, David Palacios-Martínez, Gema M. Dávila-Blázquez, Antonio Rosillo-González, José Antonio González-Posada Delgado, José Enrique Mariño-Suárez, Enrique Revilla-
Clínica e Investigación en Arteriosclerosis.2020; 32(6): 242. CrossRef
The Effect of High Carbohydrate-to-fat Intake Ratios on Hypo-HDL-cholesterolemia Risk and HDL-cholesterol Levels over a 12-year Follow-up
Hye Ah Lee, Hyoin An
Scientific Reports.2020;[Epub] CrossRef
Design and rationale of a randomized control trial testing the effectiveness of combined therapy with STAtin plus FENOfibrate and statin alone in non-diabetic, combined dyslipidemia patients with non-intervened intermediate coronary artery disease - STAFE
Taek-Geun Kwon, Albert Youngwoo Jang, Sang Wook Kim, Young Joon Hong, Jang-Ho Bae, Sung Yun Lee, Sang-Hyun Kim, Seung Hwan Han
Trials.2020;[Epub] CrossRef
Small-area variation of cardiovascular diseases and select risk factors and their association to household and area poverty in South Africa: Capturing emerging trends in South Africa to better target local level interventions
Ntabozuko Dwane, Njeri Wabiri, Samuel Manda, David Watkins
PLOS ONE.2020; 15(4): e0230564. CrossRef
Comprehensive Identification of Key Genes Involved in Development of Diabetes Mellitus-Related Atherogenesis Using Weighted Gene Correlation Network Analysis
Qi Huang, Guoxiong Deng, Rongguo Wei, Qiaoye Wang, Donghua Zou, Jinru Wei
Frontiers in Cardiovascular Medicine.2020;[Epub] CrossRef
The triglyceride-glucose index predicts ischemic heart disease risk in Koreans: a prospective study using National Health Insurance Service data
Byoungjin Park, Yong-Jae Lee, Hye Sun Lee, Dong-Hyuk Jung
Cardiovascular Diabetology.2020;[Epub] CrossRef
Prevalence of hypertriglyceridemia in adults and related cardiometabolic factors. SIMETAP-HTG study
Antonio Ruiz-García, Ezequiel Arranz-Martínez, Beatriz López-Uriarte, Montserrat Rivera-Teijido, David Palacios-Martínez, Gema M. Dávila-Blázquez, Antonio Rosillo-González, José Antonio González-Posada Delgado, José Enrique Mariño-Suárez, Enrique Revilla-
Clínica e Investigación en Arteriosclerosis (English Edition).2020; 32(6): 242. CrossRef
Incident cardiovascular disease and particulate matter air pollution in South Korea using a population-based and nationwide cohort of 0.2 million adults
Ok-Jin Kim, Soo Hyun Lee, Si-Hyuck Kang, Sun-Young Kim
Environmental Health.2020;[Epub] CrossRef
The association between low frequency of having breakfast and dyslipidemia in South Korean men and women
Doo Woong Lee, Dong-Woo Choi, Yeong Jun Ju, Sang Ah Lee, Eun-Cheol Park
European Journal of Clinical Nutrition.2019; 73(6): 896. CrossRef
Estimated glycemic load (eGL) of mixed meals and its associations with cardiometabolic risk factors among Korean adults: data from the 2013 ~ 2016 Korea National Health and Nutrition Examination Survey
Kyungho Ha, Kisun Nam, YoonJu Song
Journal of Nutrition and Health.2019; 52(4): 354. CrossRef
Working hours and nonalcoholic fatty liver disease according to sleep duration
Hwanjin Park, Soo-Jin Lee
Chronobiology International.2019; 36(12): 1671. CrossRef
An analysis of the associations between gender and metabolic syndrome components in Korean adults: a national cross-sectional study
Young-Mo Yang, Byung-Cheul Shin, Chihyoung Son, In-Hyuk Ha
BMC Endocrine Disorders.2019;[Epub] CrossRef
Time‐ and Dose‐Dependent Association of Statin Use With Risk of Clinically Relevant New‐Onset Diabetes Mellitus in Primary Prevention: A Nationwide Observational Cohort Study
Min Jung Ko, Ae Jeong Jo, Yun Jung Kim, Shin Hee Kang, Songhee Cho, Sang‐Ho Jo, Cheol‐Young Park, Sung‐Cheol Yun, Woo Je Lee, Duk‐Woo Park
Journal of the American Heart Association.2019;[Epub] CrossRef
Dyslipidemia associated with body constitution in Traditional Chinese Medicine
Qiuping Li, Qing Kong, Zihui Tang
Traditional Medicine and Modern Medicine.2019; 02(02): 59. CrossRef
Effect of Sulgidduk containing pine needle juice on lipid metabolism in high fat-cholesterol diet induced dyslipidemic rats
Yunjung Lee, Jae-Hee Park, Eunju Park
Journal of Nutrition and Health.2019; 52(1): 6. CrossRef
Increased Serum Angiopoietin-Like 6 Ahead of Metabolic Syndrome in a Prospective Cohort Study
Jun Namkung, Joon Hyung Sohn, Jae Seung Chang, Sang-Wook Park, Jang-Young Kim, Sang-Baek Koh, In Deok Kong, Kyu-Sang Park
Diabetes & Metabolism Journal.2019; 43(4): 521. CrossRef
Total cholesterol variability and risk of atrial fibrillation: A nationwide population-based cohort study
Eun Roh, Hye Soo Chung, Ji Sung Lee, Jung A. Kim, You-Bin Lee, So-hyeon Hong, Nam Hoon Kim, Hye Jin Yoo, Ji A. Seo, Sin Gon Kim, Nan Hee Kim, Sei Hyun Baik, Kyung Mook Choi, Stefan Kiechl
PLOS ONE.2019; 14(4): e0215687. CrossRef
Low Levels of Low-Density Lipoprotein Cholesterol and Mortality Outcomes in Non-Statin Users
Sung, Huh, Ryu, Lee, Scorletti, Byrne, Kim, Hyun, Ko
Journal of Clinical Medicine.2019; 8(10): 1571. CrossRef
The differential effects of changes in individual macronutrient intake on changes in lipid concentrations during childhood: From the Ewha Birth & Growth Cohort
Hye Ah Lee, Hyo Jeong Hwang, Se Young Oh, Eun Ae Park, Su Jin Cho, Hae Soon Kim, Hyesook Park
Clinical Nutrition.2018; 37(3): 1027. CrossRef
Association between cotinine‐verified smoking status and risk of nonalcoholic fatty liver disease
Nam Hee Kim, Yoon Suk Jung, Hyun Pyo Hong, Jung Ho Park, Hong Joo Kim, Dong Il Park, Yong Kyun Cho, Chong Il Sohn, Woo Kyu Jeon, Byung Ik Kim
Liver International.2018; 38(8): 1487. CrossRef
The prevalence, awareness, and treatment of lipid abnormalities in Iranian adults: Surveillance of risk factors of noncommunicable diseases in Iran 2016
Zahra Aryan, Negar Mahmoudi, Ali Sheidaei, Shahabeddin Rezaei, Zohreh Mahmoudi, Kimyia Gohari, Nazila Rezaei, Mohammad Javad Hajipour, Arezou Dilmaghani-Marand, Farideh Razi, Mahdi Sabooni, Farzad Kompani, Alireza Delavari, Bagher Larijani, Farshad Farzad
Journal of Clinical Lipidology.2018; 12(6): 1471. CrossRef
Low-carbohydrate diet and the risk of metabolic syndrome in Korean adults
K. Ha, H. Joung, Y. Song
Nutrition, Metabolism and Cardiovascular Diseases.2018; 28(11): 1122. CrossRef
Association of change in total cholesterol level with mortality: A population-based study
Su-Min Jeong, Seulggie Choi, Kyuwoong Kim, Sung-Min Kim, Gyeongsil Lee, Joung Sik Son, Jae-Moon Yun, Sang Min Park, Katriina Aalto-Setala
PLOS ONE.2018; 13(4): e0196030. CrossRef
Diabetes Fact Sheet in Korea, 2016: An Appraisal of Current Status
Jong Chul Won, Jae Hyuk Lee, Jae Hyeon Kim, Eun Seok Kang, Kyu Chang Won, Dae Jung Kim, Moon-Kyu Lee
Diabetes & Metabolism Journal.2018; 42(5): 415. CrossRef
Evaluating the prevalence, awareness, and control of hypertension, diabetes, and dyslipidemia in Korea using the NHIS-NSC database
Sunjoo Boo, Young Joo Yoon, Hyunjin Oh
Medicine.2018; 97(51): e13713. CrossRef
New and Future Parenteral Therapies for the Management of Lipid Disorders
Roberto Garcia, Jaime Burkle
Archives of Medical Research.2018; 49(8): 538. CrossRef
Association between Dietary Pattern and Incidence of Cholesterolemia in Korean Adults: The Korean Genome and Epidemiology Study
Jieul Lee, Jihye Kim
Nutrients.2018; 10(1): 53. CrossRef
Efficacy and Safety of Adding Omega-3 Fatty Acids in Statin-treated Patients with Residual Hypertriglyceridemia: ROMANTIC (Rosuvastatin-OMAcor iN residual hyperTrIglyCeridemia), a Randomized, Double-blind, and Placebo-controlled Trial
Chee Hae Kim, Kyung Ah Han, Jaemyung Yu, Sang Hak Lee, Hui Kyung Jeon, Sang Hyun Kim, Seok Yeon Kim, Ki Hoon Han, Kyungheon Won, Dong-Bin Kim, Kwang-Jae Lee, Kyungwan Min, Dong Won Byun, Sang-Wook Lim, Chul Woo Ahn, SeongHwan Kim, Young Joon Hong, Jidong
Clinical Therapeutics.2018; 40(1): 83. CrossRef
Effects of Abdominal Obesity and Risk Drinking on the Hypertension Risk in Korean Adults
Eun Sook Lee
Journal of Korean Academy of Community Health Nursing.2018; 29(3): 349. CrossRef
Does Adjuvant Treatment With Ginkgo Biloba to Statins Have Additional Benefits in Patients With Dyslipidemia?
Yu Fan, Xin Jin, Changfeng Man, Dandan Gong
Frontiers in Pharmacology.2018;[Epub] CrossRef
Relationship with Smoking and Dyslipidemia in Korean Adults
Dong Youl Shin, Young Keun Jang, Jae Hoon Lee, Jeong Hoon Wee, Dong Ho Chun
Journal of the Korean Society for Research on Nicotine and Tobacco.2017; 8(2): 73. CrossRef
Prevalence and Clinical Characteristics of Dyslipidemia in Koreans
Jee-Sun Jeong, Hyuk-Sang Kwon
Endocrinology and Metabolism.2017; 32(1): 30. CrossRef
Management Status of Cardiovascular Disease Risk Factors for Dyslipidemia among Korean Adults
Jongseok Lee, Heejeong Son, Ohk-Hyun Ryu
Yonsei Medical Journal.2017; 58(2): 326. CrossRef
Application of the 2013 American College of Cardiology/American Heart Association Cholesterol Guideline to the Korean National Health and Nutrition Examination Surveys from 1998 to 2012
Young Shin Song, Tae Jung Oh, Kyoung Min Kim, Jae Hoon Moon, Sung Hee Choi, Hak Chul Jang, Kyong Soo Park, Soo Lim
Diabetes & Metabolism Journal.2017; 41(1): 38. CrossRef
Dietary carbohydrate and fat intakes are differentially associated with lipid abnormalities in Korean adults
SuJin Song, Won O. Song, YoonJu Song
Journal of Clinical Lipidology.2017; 11(2): 338. CrossRef
Metabolic Syndrome Causes Cardiovascular Disease under Stable Statin Medication
Sang-Cheol Cho, Hoonhee Lee, Hyo-Jung Nam, Ki Hoon Han
Journal of Lipid and Atherosclerosis.2017; 6(2): 75. CrossRef
Improved trends in cardiovascular complications among subjects with type 2 diabetes in Korea: a nationwide study (2006–2013)
Chang Hee Jung, Jin Ook Chung, Kyungdo Han, Seung-Hyun Ko, Kyung Soo Ko, Joong-Yeol Park
Cardiovascular Diabetology.2017;[Epub] CrossRef
Association Between the Awareness of Dyslipidemia and Health Behavior for Control of Lipid Levels Among Korean Adults with Dyslipidemia
In Young Cho, Hwa Yeon Park, Kiheon Lee, Woo Kyung Bae, Se Young Jung, Hye Jin Ju, Jae Kyeong Song, Jong Soo Han
Korean Journal of Family Medicine.2017; 38(2): 64. CrossRef
Effect of statin on hepatocellular carcinoma in patients with type 2 diabetes: A nationwide nested case‐control study
Gyuri Kim, Suk‐Yong Jang, Eugene Han, Yong‐ho Lee, Se‐young Park, Chung Mo Nam, Eun Seok Kang
International Journal of Cancer.2017; 140(4): 798. CrossRef
Association of dietary intakes of total and subtypes of fat substituted for carbohydrate with metabolic syndrome in Koreans
Kyong Won Lee, Yoonsu Cho, Garam Jo, Yoo Kyoung Park, Min-Jeong Shin
Endocrine Journal.2016; 63(11): 991. CrossRef
Pre-treatment with simvastatin prevents the induction of diet-induced atherosclerosis in a rabbit model
Nikolaos Oikonomidis, Nikolaos Kavantzas, Laskarina-Maria Korou, Panagiotis Konstantopoulos, Vasilios Pergialiotis, Evangelos Misiakos, Ioannis Rizos, Christos Verikokos, Despina N. Perrea
Biomedical Reports.2016; 5(6): 667. CrossRef
Comparative analysis of the efficacy of omega-3 fatty acids for hypertriglyceridaemia management in Korea
H.-S. Kim, H. Kim, Y. J. Jeong, S. J. Yang, S. J. Baik, H. Lee, S.-H. Lee, J. H. Cho, I.-Y. Choi, H. W. Yim, K.-H. Yoon
Journal of Clinical Pharmacy and Therapeutics.2016; 41(5): 508. CrossRef
Parks and Green Areas Are Associated with Decreased Risk for Hyperlipidemia
Hye-Jin Kim, Jin-Young Min, Hyun-Jin Kim, Kyoung-Bok Min
International Journal of Environmental Research and Public Health.2016; 13(12): 1205. CrossRef
Analysis and comparison of statin prescription patterns and outcomes according to clinical department
H.-S. Kim, H. Kim, H. Lee, B. Park, S. Park, S.-H. Lee, J. H. Cho, H. Song, J. H. Kim, K.-H. Yoon, I. Y. Choi
Journal of Clinical Pharmacy and Therapeutics.2016; 41(1): 70. CrossRef
Dyslipidemia patterns are differentially associated with dietary factors
SuJin Song, Hee Young Paik, Minseon Park, YoonJu Song
Clinical Nutrition.2016; 35(4): 885. CrossRef
Epidemiology of dyslipidemia in Korea
Hyeon Chang Kim
Journal of the Korean Medical Association.2016; 59(5): 352. CrossRef
Difference between old and young adults in contribution of β‐cell function and sarcopenia in developing diabetes mellitus
Bo Kyung Koo, Eun Roh, Ye Seul Yang, Min Kyong Moon
Journal of Diabetes Investigation.2016; 7(2): 233. CrossRef
Economic Evaluation of Rosuvastatin and Atorvastatin for the Treatment of Dyslipidemia from a Korean Health System Perspective
Sunghwan Suh, Chang Hee Jung, Soon-Jun Hong, Jung-Sun Kim, Byung Ju Song, Hyun Soon Sohn, Sung Hee Choi
Journal of Lipid and Atherosclerosis.2016; 5(1): 61. CrossRef
Obesity and Hyperglycemia in Korean Men with Klinefelter Syndrome: The Korean Endocrine Society Registry
Seung Jin Han, Kyung-Soo Kim, Wonjin Kim, Jung Hee Kim, Yong-ho Lee, Ji Sun Nam, Ji A Seo, Bu Kyung Kim, Jihyun Lee, Jin Ook Chung, Min-Hee Kim, Tae-Seo Sohn, Han Seok Choi, Seong Bin Hong, Yoon-Sok Chung
Endocrinology and Metabolism.2016; 31(4): 598. CrossRef
Effects of mulberry leaf extract on blood glucose and serum lipid profiles in patients with type 2 diabetes mellitus: A systematic review
Seung-Ok Shin, Hyun-Ju Seo, Hyunyoung Park, Hyun Jin Song
European Journal of Integrative Medicine.2016; 8(5): 602. CrossRef
Diabetic Cardiovascular Autonomic Neuropathy Predicts Recurrent Cardiovascular Diseases in Patients with Type 2 Diabetes
Seon-Ah Cha, Jae-Seung Yun, Tae-Seok Lim, Kyoungil Min, Ki-Ho Song, Ki-Dong Yoo, Yong-Moon Park, Yu-Bae Ahn, Seung-Hyun Ko, James M Wright
PLOS ONE.2016; 11(10): e0164807. CrossRef
Effects of Age, Sex, and Menopausal Status on Blood Cholesterol Profile in the Korean Population
Ji Hye Park, Myung Ha Lee, Jee-Seon Shim, Dong Phil Choi, Bo Mi Song, Seung Won Lee, Hansol Choi, Hyeon Chang Kim
Korean Circulation Journal.2015; 45(2): 141. CrossRef
Is nutritional labeling associated with individual health? The effects of labeling-based awareness on dyslipidemia risk in a South Korean population
Jong Yeob Kim, Ki Hong Kweon, Min Jae Kim, Eun-Cheol Park, Suk-Yong Jang, Woorim Kim, Kyu-Tae Han
Nutrition Journal.2015;[Epub] CrossRef
Cost-effectiveness analysis of low density lipoprotein cholesterol-lowering therapy in hypertensive patients with type 2 diabetes in Korea: single-pill regimen (amlodipine/atorvastatin) versus double-pill regimen (amlodipine+atorvastatin)
Ji-Hyun Park, Yong-Ho Lee, Su-Kyoung Ko, Bong-Soo Cha
Epidemiology and Health.2015; 37: e2015010. CrossRef
Application of New Cholesterol Guidelines to the Korean Adult Diabetic Patients
Bu Kyung Kim, Hyeon Chang Kim, Kyoung Hwa Ha, Dae Jung Kim
Journal of Korean Medical Science.2015; 30(11): 1612. CrossRef
Undiagnosed diabetes is prevalent in younger adults and associated with a higher risk cardiometabolic profile compared to diagnosed diabetes
Yong-ho Lee, Ehrin J. Armstrong, Gyuri Kim, Jaewon Oh, Seok-Min Kang, Byung-Wan Lee, Chul Woo Ahn, Bong Soo Cha, Hyun Chul Lee, Christos S. Mantzoros, Eun Seok Kang
American Heart Journal.2015; 170(4): 760. CrossRef
New Drugs for Treating Dyslipidemia: Beyond Statins
Chang Ho Ahn, Sung Hee Choi
Diabetes & Metabolism Journal.2015; 39(2): 87. CrossRef
Can increased visceral adiposity without body weight changes accelerate carotid atherosclerosis in South Korean participants with type 2 diabetes?
Chul Sik Kim, Soo-Kyung Kim, Maria Rosario G. Araneta, Eun Jig Lee, Elizabeth Barrett-Connor, Kab Bum Huh
Journal of Diabetes and its Complications.2015; 29(8): 1085. CrossRef
Prevalence and Management of Dyslipidemia Among Korean Adults: KNHANES 2010-2012
Sungok Jang, Jongseok Lee
Journal of the Korea Academia-Industrial cooperation Society.2015; 16(11): 7978. CrossRef
Prevalence and Gender-Related Characteristics of Metabolic Syndrome in Korean Community
Kyung-Taek Park, Hack-Lyoung Kim, Sang-Hyun Kim, Myung-A Kim, Euijae Lee, Jonghanne Park, Sang-Ho Jo, Sung Rae Kim, Jaetaek Kim, Chee Jeong Kim, Moon-Kyu Lee, Hyun Ho Shin
Journal of Lipid and Atherosclerosis.2014; 3(2): 89. CrossRef

First
Prev
Page of 1
Next
Last

Search